Recent publications highlight advances in mitochondrial injury, hemorrhagic shock, and ischemia-reperfusion research.
Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock.
Patel N, Johnson MA, Vapniarsky N, Van Brocklin MW, Williams TK, Youngquist ST, Ford R, Ewer N, Neff LP, Hoareau GL.
Sci Rep. 2023;13(1):4496.
Esmolol reduces myocardial injury induced by resuscitative endovascular balloon occlusion of the aorta (REBOA) in a porcine model of hemorrhagic shock.
Hoareau GL, Beyer CA, Caples CM, Spruce MW, Gilbert Z, Grayson JK, Neff LP, Williams TK, Johnson MA.
Injury. 2020;51(10):2165-2171.
Not ready for prime time: Intermittent versus partial resuscitative endovascular balloon occlusion of the aorta for prolonged hemorrhage control in a highly lethal porcine injury model.
Johnson MA, Hoareau GL, Beyer CA, Caples CA, Spruce M, Grayson JK, Neff LP, Williams TK.
J Trauma Acute Care Surg. 2020;88(2):298-304.
Ectonucleotidases in Ischemia Reperfusion Injury: Unravelling the Interplay With Mitochondrial Dysfunction in Liver Transplantation.
Nwaduru C, Ovalle LA, Hoareau GL, Baker E, Buff M, Selim M, Baker TB, Zimmerman MA.
Transplant Proc. 2024;56(7):1598-1606.